New 64-Bit beta drivers for Windows Vista extend extend compatibility.
The MasterControl and iO|26 studio interfaces and MultiMix FireWire mixers are now compatible with 64-bit Windows Vista computer operating systems. With these updates, you can integrate Alesis FireWire equipment into virtually any computer setup whether you use Mac OS X, Windows XP, or Windows Vista.
You can download the 64-bit Windows Vista updates for free from the Docs and Downloads tabs at the following pages:
iO|14 or iO|26